Histone H3 K9ac Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Search, find, compare suppliers for anti-Histone H3 K9ac antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Histone H3 K9ac |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, C. elegans |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 50 µg |
| Concentration | 0.68 mg/ml |
| Applications | Chip, Immunohistochemistry, IF Microscopy, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-Histone H3 [ac Lys9] was affinity purified from monospecific antiserum by immunoaffinity chromatography. This antibody reacts with human Histone H3.2. A BLAST analysis was used to suggest cross-reactivity with Human, mouse, and C. elegans. Predicted to react with many species including rat, chicken, Xenopus, Drosophila, and plant based on 100% sequence homology. Cross-reactivity with Histone H3 from other sources has not been determined. Acetylation of histone H3 at the K9 residue is associated with chromosome condensation in mitotic cells. The presence of H3K9ac is correlated to H3K4 trimethylation, and their distribution is related to developmentally repressed genes in some species. It has been shown that neuron depolarization promotes intragenic histone acetylation leading toward the formation of this modification. In pituitary, dopamine receptor agonists lead toward apoptosis. However, in tumors, decreased availability and activity of these agonists, combined with decreased H3K9ac leads toward resistance to chemotherapies and cancer survival and proliferation. Nuclear receptor PPAR ' induces the enrichment of H3K9ac enrichment on downstream promoters, which has effects on transcription and ultimately nuclear receptor transactivation. Anti-Histone H3 are ideal for researchers interested in Chromatin Modifiers, Chromatin Research, Histones and Modified Histones, and Epigenetics research. |
| Immunogen | Histone H3 [ac Lys9] affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic acetylated peptide surrounding Lysine 9 of human Histone H3.2. |
| Other Names | rabbit anti-Histone H3 Ac Lys9 antibody, H3.3B, H3 histone, family 3A, H3.3AH3F3H3F3B, histone H3.3, MGC87783, MGC87782, H3K9ac |
| Gene, Accession # | HIST2H3C, Gene ID: 126961, NCBI: NP_001005464, UniProt: Q71DI3 |
| Catalog # | 600-401-I72 |
| Price | $495 |
| Order / More Info | Histone H3 K9ac Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | PubMed: 29123096 |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
Profile of ROCKLAND IMMUNOCHEMICALS INC.
Return to Antibodies