Edit |   |
---|---|
Antigenic Specificity | Neuroligin 1 |
Clone | S97A-31 |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | PerCP conjugate |
Size | 100 µg |
Concentration | 1mg/mL |
Applications | ELISA, Immunohistochemistry, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-Neuroligin 1 Antibody was purified from concentrated tissue culture supernate by Protein G chromatography. BLAST analysis suggests that it is 99% identical to mouse, 99% identical to human and >50% identical to Neuroligin-2 and -3. Neuroligin-1 is a neuronal cell surface protein belonging to the type-B carboxylesterase/lipase family. It is a necessary component in the maturation of excitatory synapses for their normal, functional development, and is necessary to the regulation of synaptic plasticity and the development of long-term memory within the adult amygdala in mammals. It is believed to participate in cell-cell-interaction through the assembly of intracellular junction by the binding of beta-neurexins, and may also be a factor in the maintenance and assembly of synaptic junctions. It is also thought to have involvement in excitatory synaptic specification. Within brain tissue, Neuroligin-1 is primarily observed in neurons and spinal cord. Anti-Neuroligin-1 is ideal for research in Neuroscience, including narcolepsy and synaptic neurotransmission: GABAergic inhibition, as well as Cell Adhesion. |
Immunogen | Anti-Neuroligin 1 Antibody was produced by repeated immunization of mice with a fusion protein containing amino acids 718-843 of rat Neuroligin-1. |
Other Names | NLG 1, KIAA1070, MGC45115, Neuroligin-1, NL1, NLG1, Nlgn1 |
Gene, Accession # | Nlgn1, Gene ID: 116647, NCBI: NP_446320, UniProt: Q62765 |
Catalog # | 200-365-W75 |
Price | $495 |
Order / More Info | Neuroligin 1 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |