GRP78 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | GRP78 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat, bovine, cryphonectria parasitica, hamster, monkey, rabbit, Xenopus |
| Isotype | n/a |
| Format | serum |
| Size | 200 µL |
| Concentration | 85 mg/mL |
| Applications | IF Microscopy, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-GRP78 Antibody was prepared from monospecific antiserum by delipidation and defibrination. A BLAST analysis was used to suggest cross-reactivity with GRP78 from Human, Mouse, Rat, Cow, Fungus (Cryphonectria parasitica), Hamster, Monkey, Rabbit, Xenopus based on 100% homology with the immunizing sequence. Cross-reactivity with GRP78 from other sources has not been determined. Heat Shock research. GRP78 is a ubiquitously expressed, 78-kDa glucose regulated protein, and is commonly referred to as an immunoglobin chain binding protein (BiP). The BiP proteins are categorized as stress response proteins because they play an important role in the proper folding and assembly of nascent protein and in the scavenging of misfolded proteins in the endoplasmic reticulum lumen. Translation of BiP is directed by an internal ribosomal entry site (IRES) in the 5' nontranslated region of the BiP mRNA. BiP IRES activity increases when cells are heat stressed. GRP78 is also critical for maintenance of cell homeostasis and the prevention of apoptosis. Luo et al. have provided findings that suggest GRP78 is essential for embryonic cell growth and pluripotent cell survival. |
| Immunogen | Grp78 Antibody was produced from whole rabbit serum prepared by repeated immunizations with rat GRP78 (Bip) synthetic peptide conjugated to KLH. |
| Other Names | BiP, Grp78, HspA5, MIF2, immunoglobulin heavy chain binding protein, 78 kDa glucose-regulated protein, Heat shock 70 kDa protein 5, Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78 |
| Gene, Accession # | Hspa5, Gene ID: 25617, NCBI: NP_037215.1, UniProt: P06761 |
| Catalog # | 100-401-F38 |
| Price | $475 |
| Order / More Info | GRP78 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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