DRAK1 Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityDRAK1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatimmunoaffinity purified
Size100 µg
Concentration1 mg/mL
ApplicationsELISA, IF Microscopy, Western Blot
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DescriptionAnti-DRAK1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. No cross responses to DRAK2, DAP or ZIP kinases. Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as ASK-1 and RIP, are mediators of apoptosis. Two novel serine/threonine kinases that induce apoptosis were recently identified and designated DRAK1 and DRAK2 for DAP kinase-related apoptosis-inducing protein kinases. DRAKs contain an N-terminal kinase domain and a C-terminal regulation domain. Overexpression of DRAK1 induces apoptosis. DRAKs have high sequence homology to DAP and ZIP kinases, and they represent a novel family of serine/threonine kinases, which mediates apoptosis through their catalytic activities. DRAK1 is located in nucleus and the messenger RNA was ubiquitously expressed in human tissues.
ImmunogenAnti-DRAK1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a peptide corresponding to amino acids near the N-terminus of human DRAK1.
Other NamesDRAK1 Antibody, DRAK1, DRAK1, DAP kinase-related apoptosis-inducing protein kinase 1
Gene, Accession #STK17A, Gene ID: 9263, NCBI: NP_004751.2, UniProt: Q9UEE5
Catalog #600-401-AX7
Price$475
Order / More InfoDRAK1 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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