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Antigenic Specificity | DRAK1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-DRAK1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. No cross responses to DRAK2, DAP or ZIP kinases. Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as ASK-1 and RIP, are mediators of apoptosis. Two novel serine/threonine kinases that induce apoptosis were recently identified and designated DRAK1 and DRAK2 for DAP kinase-related apoptosis-inducing protein kinases. DRAKs contain an N-terminal kinase domain and a C-terminal regulation domain. Overexpression of DRAK1 induces apoptosis. DRAKs have high sequence homology to DAP and ZIP kinases, and they represent a novel family of serine/threonine kinases, which mediates apoptosis through their catalytic activities. DRAK1 is located in nucleus and the messenger RNA was ubiquitously expressed in human tissues. |
Immunogen | Anti-DRAK1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a peptide corresponding to amino acids near the N-terminus of human DRAK1. |
Other Names | DRAK1 Antibody, DRAK1, DRAK1, DAP kinase-related apoptosis-inducing protein kinase 1 |
Gene, Accession # | STK17A, Gene ID: 9263, NCBI: NP_004751.2, UniProt: Q9UEE5 |
Catalog # | 600-401-AX7 |
Price | $475 |
Order / More Info | DRAK1 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |