IL-17A Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityIL-17A
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesmouse, rat
Isotypen/a
Formatbiotin conjugate
Size100 µg
Concentration1.0 mg/mL
ApplicationsELISA, Immunohistochemistry, Western Blot
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DescriptionIn ELISA and other immunoreactive assays, this antibody will recognize both native and recombinant rat IL17-A in cell supernatants and certain body fluids. A control of similarly diluted normal rabbit IgG is recommended. Rat IL17-A (also known as Interleukin-17, Cytotoxic T-lymphocyte-associated antigen 8 and CTLA-8) is a proinflammatory cytokine member of a six-species family of proteins (IL-17A-17F). Rat IL-17A protein is a homodimer consisting of two 134 amino acids peptides. IL-17A is secreted mainly by activated CD4+ and CD8+ T lymphocytes and acts through its receptor, IL-17R, to induce the expression of many mediators of inflammation, most strikingly, those that are involved in the proliferation, maturation and chemotaxis of neutrophils. Elevated levels of IL-17A have been associated with several conditions, including rheumatoid arthritis, airway inflammation, allograft rejection, inflammatory bowel disease, psoriasis, cancer and multiple sclerosis. There is 58% identity between the amino acid sequence of human and rat IL-17A. Anti-IL-17A antibody is ideal for investigators involved in Immunology research.
ImmunogenThis purified antibody was prepared from whole rabbit serum produced by repeated immunizations with full length recombinant rat IL17-A protein.
Other Namesrabbit anti-IL-17A biotin Conjugated Antibody, rabbit anti-Interleukin-17A biotin Conjugated Antibody, Interleukin17, IL-17, Cytotoxic T-lymphocyte-associated antigen 8 and CTLA-8
Gene, Accession #Il17a, Gene ID: 301289, NCBI: Q61453.1, UniProt: Q61453
Catalog #212-406-B32
Price$455
Order / More InfoIL-17A Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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