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Antigenic Specificity | BAFF |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | ion exchange purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-BAFF Antibody was Ion exchange chromatography purified. A BLAST analysis was used to suggest cross-reactivity with BAFF with Human, Mouse and Rat based on 100% homology with the immunizing sequence. Cross-reactivity with BAFF from other sources has not been determined. BAFF antibody detects human BAFF. Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated BAFF (for B cell Activating Factor belonging to the TNF Family), BLyS (for B Lymphocyte Stimulator), TALL-1 (for TNF- and ApoL-related Leukocyte-expressed Ligand), and THANK (for TNF Homologue that Activate Apoptosis, NF-alpha;B and c-jun N-terminal Kinase). BAFF/BLyS was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion. Three receptors for BAFF were recently identified and designated TACI, BCMA and BAFF-R. BAFF and its receptors are essential for B cell development, survival, and humoral immune responses. BAFF is involved in the development of autoimmune diseases including systemic lupus erythaematosus and rheumatoid arthritis. Anti-BAFF antibodies are ideal for investigators involved in NFkappaB, Cytokine and Growth Factor research. |
Immunogen | BAFF Antibody was produced from whole rabbit serum prepared by repeated immunizations with a peptide corresponding to amino acids near the c-terminus of human BAFF. |
Other Names | BAFF, BLYS, TALL1, TNFSF20, ZTNF4 |
Gene, Accession # | TNFSF13B, Gene ID: 10673, NCBI: NP_001139117.1, UniProt: Q9Y275 |
Catalog # | 200-401-G83 |
Price | $475 |
Order / More Info | BAFF Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |