ZSCAN4 Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityZSCAN4
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunoaffinity purified
Size100 µg
Concentration1.0mg/mL
ApplicationsELISA, Immunohistochemistry, IF Microscopy, Western Blot
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DescriptionAnti-ZSCAN4 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with ZSCAN4 from other sources has not been determined. Zytotic genome activation (ZGA) is the first and most critical transition event from the maternal genetic to the embryonic genetic program and the major burst of ZGA occurs only in the late 2-cell stage. ZSCAN4 encodes a SCAN domain and four zinc finger domains and is expressed in late 2-cell embryos and embryonic stem cells. Loss-of-function studies using siRNA shows delays in the progression from the 2-cell to the 4-cell stage and subsequent embryo development. ZSCAN4 plays an important role in the preimplantation development. Also, ZSCAN4 is involved in telomere maintenance and long term genomic stability in ES cells, suggesting that ZSCAN4 may be of critical importance in maintaining pluripotency in replicating stem cells.
ImmunogenAnti-ZSCAN4 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 18 amino acid synthetic peptide near the C-terminus of human ZSCAN4.
Other NamesZSCAN4 Antibody, ZNF494, ZNF494, Zinc finger and SCAN domain-containing protein 4, Zinc finger protein 494
Gene, Accession #ZSCAN4, Gene ID: 201516, NCBI: NP_689890.1, UniProt: Q8NAM6
Catalog #600-401-GG8
Price$475
Order / More InfoZSCAN4 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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