AIM Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityAIM
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatimmunoaffinity purified
Size100 µg
Concentration1.0 mg/ml
ApplicationsELISA, Immunohistochemistry, Western Blot
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DescriptionAnti-AIM Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with AIM from other sources has not been determined. Apoptosis inhibitor of macrophages (AIM) is a member of the scavenger receptor cysteine-rich domain superfamily (SRCR-SF) initially identified as an inducible cell surface ligand of CD5. It was shown that AIM functions in the thymus as the inducer of resistance to apoptosis within CD4+/CD8+ thymocytes and as the supporter of the viability of these cells before thymic selection. AIM was also shown to support macrophage survival and enhance their phagocytic function. More recent experiments using recombinant AIM significantly inhibited apoptosis of NKT and T cells obtained from C. parvum-stimulated livers in vitro, suggesting that AIM functions to induce resistance to apoptosis in these cells and supports host defense against inflammation during infection.
ImmunogenAnti-AIM antibody was prepared from whole rabbit serum produced by repeated immunizations with a 13 amino acid synthetic peptide near the C-terminus of human AIM.
Other NamesAIM Antibody, AIM, API6, PRO229, Spalpha, SP-ALPHA, UNQ203/PRO229, CD5 antigen-like, CT-2
Gene, Accession #CD5L, Gene ID: 922, NCBI: AAD01446, UniProt: O43866
Catalog #600-401-X88
Price$475
Order / More InfoAIM Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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