CIITA Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityCIITA
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatserum
Size100 µL
Concentration90 mg/mL
ApplicationsELISA, Western Blot
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DescriptionAnti-CIITA antibody was prepared from monospecific antiserum by delipidation and defibrination. Anti-CIITA antibody detects CIITA. The transactivator CIITA regulates basal and interferon-induced expression of Major Histocompatibility Complex class II genes. CIITA restores expression of all MHC class II gene expression in mutant cells and corrects regulatory defects of MHC class II genes. Antibodies to this transactivator are useful in the study of diseases of pathological MHC class II expression. Antigen can be obtained from Raji cell lysates. Typically levels of CIITA expression are too low to detect endogenous levels of protein expression. Transiently transfected cells are usually employed to study this transcription factor.
ImmunogenThe immunogen used for this study was a bacterially produced recombinant FLAG-CIITA corresponding to amino acids 1 through 333 of the human protein.
Other Namesrabbit anti-CIITA Antibody, MHC class II transactivator, CIITA, MHC2TA
Gene, Accession #CIITA, Gene ID: 4261, NCBI: NP_000237.2, UniProt: P33076
Catalog #100-401-249
Price$475
Order / More InfoCIITA Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific ReferencesPubMed: 11413136 // 17088550 // 18493979 // 18662994 // 25753668 // 31753848 // 33863790 // 34352044
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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