GFR alpha 3 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | GFR alpha 3 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | DEAE purified |
| Size | 100 µg |
| Concentration | 1 mg/mL |
| Applications | ELISA, Immunohistochemistry, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-GFR alpha 3 Antibody is purified by DEAE purification methods. Cross reactivity with GFR alpha 3 from other sources has not been determined. Members of the glial cell line-derived neurotrophic factor (GDNF) family, including GDNF and neurturin (NTN) play essential roles in the control of vertebrate neuron survival and differentiation. A new member of the GDNF family was recently identified and designated persephin. Physiological responses to these neurotrophic factors require two receptor subunits, the novel glycosylphosphadidylinositol linked protein GFRa and Ret receptor tyrosine kinase GFRbeta. Following the findings of GFRa-1 and -2, a novel receptor in GFRa family was identified very recently from human and mouse and designated GFRa-3. GFRa-3 binds persephin, thus, persephin, GFRa-3, and Ret PTK form a complex to transduce persephin signal and to mediate persephin function. |
| Immunogen | Anti-GFR alpha 3 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 14 amino acid peptide near the internal region of murine GFR alpha 3. |
| Other Names | GFR alpha 3 Antibody, Y15110, GFRalpha3, GDNF family receptor alpha-3, GDNF receptor alpha-3 |
| Gene, Accession # | Gfra3, Gene ID: 14587, NCBI: ab008833, UniProt: O35118 |
| Catalog # | 200-401-BK7 |
| Price | $475 |
| Order / More Info | GFR alpha 3 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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