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Antigenic Specificity | PTK7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-PTK7 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with PTK7 from other sources has not been determined. Protein-tyrosine kinases (PTKs) play important roles in regulating cell proliferation and differentiation during development. One member of the PTK family, PTK7, has been suggested to regulate the planar cell polarity (PCP) pathway in vertebrates and may play a role in neural convergent extension and neural tube closure. PTK7 has also been implicated in the development of cancer. Loss of PTK7 expression was seen in several melanoma cell lines and biopsies. Conversely, high-throughput analysis of acute myeloid leukemia samples showed an increased level of PTK7 expression compared to normal bone marrow and purified CD34+ cells. Multiple isoforms of PTK7 are known to exist. |
Immunogen | Anti-PTK7 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 15 amino acid synthetic peptide from near the N-terminus of human PTK7. |
Other Names | PTK7 Antibody, CCK4, CCK-4, CCK4, Inactive tyrosine-protein kinase 7, Colon carcinoma kinase 4 |
Gene, Accession # | PTK7, Gene ID: 5754, NCBI: AAH71557, UniProt: Q13308 |
Catalog # | 600-401-DU7 |
Price | $475 |
Order / More Info | PTK7 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |