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Antigenic Specificity | ZMYM2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-ZMYM2 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. At least two isoforms of ZMYM1 are known to exist; this antibody will detect only the shorter isoform. ZMYM1 antibody is predicted to not cross-react with other ZMYM protein family members. Zinc-finger proteins contain DNA-binding domains characterized by the unique role of zinc and have a wide variety of functions such as transcriptional activation or repression. The protein folding and the DNA binding ability are governed by the coordination of a zinc ion. As a member of the MYM (myeloproliferative and mental retardation) gene family, ZMYM1 is widely expressed in different tissues in eukaryotes under several forms derived by alternative splicing. While its function remains unknown, the related protein ZMYM2 has been shown to associate with and stabilize the LSD1-CoREST-HDAC1 (LCH) complex of chromatin through its MYM-type zinc fingers, thereby enhancing the transcriptional repression of several genes, suggesting that ZMYM1 may play a similar role. |
Immunogen | Anti-ZMYM1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 17 amino acid synthetic peptide near the C-terminus of human ZMYM1. |
Other Names | ZMYM2 Antibody, FIM, MYM, RAMP, SCLL, ZNF198, FIM, Zinc finger MYM-type protein 2, Fused in myeloproliferative disorders protein |
Gene, Accession # | ZMYM2, Gene ID: 7750, NCBI: NP_001177893.1, UniProt: Q9UBW7 |
Catalog # | 600-401-GF7 |
Price | $475 |
Order / More Info | ZMYM2 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |