ETO Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | ETO |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | serum |
| Size | 100 µL |
| Concentration | neat |
| Applications | ELISA, Chip |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-ETO Antibody is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration. This product reacts with human ETO. Cross reactivity with ETO from other sources is not known. ETO is a transcriptional regulator which belongs to the myeloid translocation gene family. ETO exerts its function by interaction with transcription factors bound to promoters and binding to histone deacetylases. It recruits a range of corepressors to facilitate transcriptional repression. The t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities in acute myeloid leukemia. This translocation produces a chimeric gene made up of the 5'-region of AML1 and the 3'-region of the ETO gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Anti-ETO Antibody is ideal for research in Gene Expression, Transcription and Cancer. |
| Immunogen | Anti-ETO Antibody was produced in rabbits by repeated immunizations with human ETO using two synthetic peptides containing sequences from the N-terminal and internal region of the protein respectively. |
| Other Names | Protein CBFA2T1, Cyclin-D-related protein, Eight twenty one protein, Protein ETO, Protein MTG8, Zinc finger MYND domain-containing protein 2, AML1T1, CBFA2T1, CDR, ETO, MTG8, ZMTND2 |
| Gene, Accession # | RUNX1T1, Gene ID: 862, NCBI: NP_001185554.1, UniProt: Q06455 |
| Catalog # | 100-401-V08 |
| Price | $475 |
| Order / More Info | ETO Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
Profile of ROCKLAND IMMUNOCHEMICALS INC.