SIRT4 Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificitySIRT4
Clonepolyclonal
Host SpeciesChicken
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunoaffinity purified
Size100 µg
Concentration1.0 mg/ml
ApplicationsELISA, Western Blot
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DescriptionAnti-SIRT4 Antibody is an IgY fraction that has been affinity purified by immunoaffinity purification. Cross reactivity with SIRT4 from other sources has not been determined. The Silent Information Regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and have important functions in the regulation of metabolism, growth and differentiation, inflammation, cellular survival, as well as in senescence and lifespan extension. Sirtuins, including SIRT1-7, are human homologs of yeast Sir2p. Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) which regulate cellular metabolism, e.g. energy metabolism, and thereby are associated with aging and several age-related diseases. SIRT4 localizes to mitochondria, inhibits glutamate dehydrogenase, and is thought to be involved in the regulation of insulin secretion.
ImmunogenAnti-SIRT4 antibody was prepared from chicken egg fractions produced by repeated immunizations with a 17 amino acid synthetic peptide near the N-terminus of human SIRT4.
Other NamesSIRT4 Antibody, SIR2L4, SIR2L4, NAD-dependent protein deacetylase sirtuin-4, NAD-dependent ADP-ribosyltransferase sirtuin-4
Gene, Accession #SIRT4, Gene ID: 23409, NCBI: EAW98182, UniProt: Q9Y6E7
Catalog #200-901-EL9
Price$475
Order / More InfoSIRT4 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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