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Antigenic Specificity | SIRT4 |
Clone | polyclonal |
Host Species | Chicken |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1.0 mg/ml |
Applications | ELISA, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-SIRT4 Antibody is an IgY fraction that has been affinity purified by immunoaffinity purification. Cross reactivity with SIRT4 from other sources has not been determined. The Silent Information Regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and have important functions in the regulation of metabolism, growth and differentiation, inflammation, cellular survival, as well as in senescence and lifespan extension. Sirtuins, including SIRT1-7, are human homologs of yeast Sir2p. Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) which regulate cellular metabolism, e.g. energy metabolism, and thereby are associated with aging and several age-related diseases. SIRT4 localizes to mitochondria, inhibits glutamate dehydrogenase, and is thought to be involved in the regulation of insulin secretion. |
Immunogen | Anti-SIRT4 antibody was prepared from chicken egg fractions produced by repeated immunizations with a 17 amino acid synthetic peptide near the N-terminus of human SIRT4. |
Other Names | SIRT4 Antibody, SIR2L4, SIR2L4, NAD-dependent protein deacetylase sirtuin-4, NAD-dependent ADP-ribosyltransferase sirtuin-4 |
Gene, Accession # | SIRT4, Gene ID: 23409, NCBI: EAW98182, UniProt: Q9Y6E7 |
Catalog # | 200-901-EL9 |
Price | $475 |
Order / More Info | SIRT4 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |