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Antigenic Specificity | Histone H3 K9-Ac/phospho S10 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 50 µg |
Concentration | 0.25 mg/mL |
Applications | IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-Histone H3 K9Ac/pS10 was affinity purified from monospecific antiserum by immunoaffinity chromatography. This antibody reacts with human Histone H3. Cross-reactivity with other sources has not been determined. Histones of the nucleosome build chromatin and undergo various post-translational modifications proven to regulate chromatin condensation and DNA accessibility. Phosphorylations on Serine 10 has been shown to facilitate chromatin condensation by its interaction with Aurora-B kinase during mitosis and is alternatively active in cell division. Serine modification is associated with IKK-alpha and Snf1 enzymes in transcriptional activation, and is modified by MSK1 and 2 which are enzymes that react to growth factors and cellular stress in immediate-early gene activation. Lysine 9 acetylations are connected with histone deposition and transcriptional activation. Anti-Histone H3 [ac Lys9/phospho Ser10] antibody is ideal for researchers interested in Chromatin Modifiers, Chromatin Research, Histones and Modified Histones, and Epigenetics research. |
Immunogen | Anti-Histone H3 [ac Lys9/phospho Ser10] affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide with a acetylation surrounding Lysine 9 and a phosphorylation surrounding serine 10 of human Histone H3. |
Other Names | rabbit anti-Histone H3 Ac Lys9 pS10 antibody, Histone H3 antibodies, H3K9ac/pS10 |
Gene, Accession # | HIST2H3C, Gene ID: 126961, NCBI: NP_001005464, UniProt: Q71DI3 |
Catalog # | 600-401-P08 |
Price | $495 |
Order / More Info | Histone H3 K9-Ac/phospho S10 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |