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Antigenic Specificity | KLHL1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-KLHL1 Antibody is immunoaffinity purified. Cross reactivity with KLHL1 from other sources has not been determined. The mammalian Kelch-like 1 (KLHL1) was initially discovered as a homolog to the Drosophila Kelch gene that is highly expressed in several brain tissues. The predicted protein domain structure of KLHL1 is characteristic of a number of proteins that bind actin, form dimers, and often act as actin-organizing proteins. Based on the presence of anti-sense RNA that spans the transcription and translation start sites as well as the first splice site of KLHL1 in brain tissue of individuals suffering from the neurodegenerative disorder spinocerebellar ataxia type 8 (SCA8), it has been suggested that KLHL1 is involved this disease and that regulation of KLHL1 protein may be affected by antisense RNA expression. |
Immunogen | Anti-KLHL1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 14 amino acid synthetic peptide from near the amino-terminus of human KLHL1. |
Other Names | KLHL1 Antibody, MRP2, KIAA1490, Kelch-like protein 1 |
Gene, Accession # | KLHL1, Gene ID: 57626, NCBI: AAF81719, UniProt: Q9NR64 |
Catalog # | 600-401-CF1 |
Price | $475 |
Order / More Info | KLHL1 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |