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Antigenic Specificity | Synaptobrevin (VAMP) |
Clone | SP10 |
Host Species | Mouse |
Reactive Species | human, mouse, rat, bovine, hamster, porcine, rabbit |
Isotype | IgM |
Format | supernatant |
Size | 100 µL |
Concentration | n/a |
Applications | Immunohistochemistry, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-Synaptobrevin (VAMP) Antibody is directed against human synaptobrevin. Anti-Synaptobrevin was IgM purified by chromatography from cell culture supernatant. Reactivity is expected against bovine, mouse, pig, rat, rabbit and hamster. Synaptobrevin (also VAMP) is an integral membrane protein of synaptic vesicles that plays a major role in the formation of larger SNARE complexes, along with SNAP-25 and syntaxin. Synaptobrevin has been shown to be essential for two fast synapse-specific membrane trafficking processes: fast exocytosis for neurotransmitter release and fast endocytosis that mediates rapid recycling of synaptic vesicles. Decreased levels of synaptobrevin in human hippocampus and cortex have been correlated with cognitive defects in Alzheimer's disease. |
Immunogen | Anti-Synaptobrevin (VAMP) Monoclonal Antibody was produced in mouse by repeated immunizations with synaptic immunoprecipitate (crude) from human brain. |
Other Names | SYB1, Synaptobrevin, vesicle associated membrane protein, Vesicle-associated membrane protein 1, VAMP-1, Synaptobrevin-1, VAMP1, Vesicle-associated membrane protein 2, VAMP-2, Synaptobrevin-2, VAMP2, SYB2 |
Gene, Accession # | VAMP1/2, Gene ID: 6843, NCBI: AAH23286.1, UniProt: P23763 |
Catalog # | 200-301-E34 |
Price | $485 |
Order / More Info | Synaptobrevin (VAMP) Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |