AIFM3 Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityAIFM3
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunoaffinity purified
Size100 µg
Concentration1 mg/mL
ApplicationsELISA, Western Blot
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DescriptionAnti-AIFM3 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with AIFM3 from other sources has not been determined. Apoptosis, also known as programmed cell death, plays major roles in development and normal tissue turnover in addition to tumor formation. Recently a protein similar to the apoptosis-inducing factor (AIF) was cloned and designated AIFL (also known as AIFM3). AIFM3 is expressed ubiquitously and is predominantly localized to the inner membranes of mitochondria. Unlike AIF, AIFM3 does not translocate to the nucleus upon induction of apoptosis. However, overexpression of AIFM3, like AIF, induced cytochrome c release from the mitochondria, cleavage of caspase 3, and ultimately apoptosis, indicating AIFM3 induces apoptosis through caspase activation. Multiple isoforms of AIFM3 are known to exist.
ImmunogenAnti-AIFM3 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 16 amino acid synthetic peptide from near the internal region of human AIFM3.
Other NamesAIFM3 Antibody, AIFL, AIFL, Apoptosis-inducing factor 3, Apoptosis-inducing factor-like protein
Gene, Accession #AIFM3, Gene ID: 150209, NCBI: NP_001018070.1, UniProt: Q96NN9
Catalog #600-401-X86
Price$475
Order / More InfoAIFM3 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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