Edit |   |
---|---|
Antigenic Specificity | KPNA7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-KPNA7 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. KPNA7 antibody is human specific. KPNA7 antibody is predicted to not cross-react with other Importin alpha family members. Karyopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex (NPC) by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. KPNA7 is most closely related to KPNA2, but unlike KPNA2, KPNA7 primarily localizes to the nucleus. It has been suggested that KPNA7 may play a role in the transport of essential nuclear proteins required for early embryogenesis. |
Immunogen | Anti-KPNA7 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 13 amino acid synthetic peptide near the N-terminus of human KPNA7. |
Other Names | KPNA7 Antibody, Importin subunit alpha-8, Karyopherin subunit alpha-7 |
Gene, Accession # | KPNA7, Gene ID: 402569, NCBI: NP_001139187, UniProt: A9QM74 |
Catalog # | 600-401-CG6 |
Price | $475 |
Order / More Info | KPNA7 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |