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Antigenic Specificity | West Nile Virus Envelope |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1.0 mg/mL |
Applications | ELISA |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-West Nile Virus Envelope Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with West Nile Virus Envelope from other sources has not been determined. West Nile Virus (WNV) is a member of the Flaviviridae, a plus-stranded virus family that includes St. Louis encephalitis virus, yellow fever virus, and Dengue virus. WNV was initially isolated in 1937 in the West Nile region of Uganda and has become prevalent in Africa, Asia, and Europe. It has rapidly spread across the United States with cases being observed in every continental state. Virus particles consist of a dense core made up of the core/capsid protein encapsulating the RNA genome surrounded by a membrane envelope embedded with envelope and matrix proteins. While the viral core protein is thought to contribute to the WNV-associated inflammation via apoptosis induced though the caspase-9 pathway, the highly glycosylated envelope protein plays a major role for WNV entry into target cells as this entry can be inhibited by using a recombinant domain III from the envelope glycoprotein. The WNV receptor has recently been identified as alpha v beta 3 integrin. |
Immunogen | Anti-West Nile Virus envelope antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to 16 amino acids at the N terminus of the West Nile virus envelope protein. |
Other Names | West Nile Virus Envelope Antibody, Genome polyprotein, Core protein, NS1 |
Gene, Accession # | WNVgp1, Gene ID: 912267, NCBI: NP_776012, UniProt: P06935 |
Catalog # | 600-401-FY5 |
Price | $475 |
Order / More Info | West Nile Virus Envelope Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |