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Antigenic Specificity | Collagen Type VI |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, bovine |
Isotype | n/a |
Format | peroxidase (HRP) conjugate |
Size | 50 µg |
Concentration | 1.0 mg/mL |
Applications | ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-Collagen VI has been prepared by immunoaffinity chromatography using immobilized antigens followed by extensive cross-adsorption against other collagens, human serum proteins and non-collagen extracellular matrix proteins to remove any unwanted specificities. Some class specific anti-collagens may be specific for three-dimensional epitopes which may result in diminished reactivity with denatured collagen or formalin-fixed, paraffin embedded tissues. This antibody reacts with most mammalian Type VI collagens and has negligible cross-reactivity with Type I, II, III, IV and V collagens. Non-specific cross reaction of anti-collagen antibodies with other human serum proteins or non-collagen extracellular matrix proteins is negligible. Collagen Type VI Peroxidase Conjugated Antibody is specific for collagen type VI protein. The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI) chains. The alpha2(VI) and alpha3(VI) chains are encoded by the COL6A2 and COL6A3 genes, respectively. The protein encoded by this gene is the alpha 1 subunit of type VI collagen (alpha1(VI) chain). Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy. |
Immunogen | Collagen Type VI from human and bovine placenta |
Other Names | rabbit anti-Collagen Type VI antibody peroxidase conjugation, HRP conjugated rabbit anti-Collagen Type VI antibody, Collagen alpha-1 (VI) chain, Collagen VI antibody, Human mRNA for collagen VI alpha 1 C terminal globular domain antibody |
Gene, Accession # | COL6A1-COL6A3, Gene ID: 1291, NCBI: AAH52575.1, UniProt: P12109 |
Catalog # | 600-403-108 |
Price | $495 |
Order / More Info | Collagen Type VI Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |