Edit |   |
---|---|
Antigenic Specificity | TAF10 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1.08 mg/ml |
Applications | ELISA, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This affinity-purified antibody is directed against human TAF10 protein. The product was affinity purified from monospecific antiserum by immunoaffinity purification. A BLAST analysis was used to suggest cross reactivity with TAF10 protein from human and mouse (100% homology). Reactivity against homologues from other sources is not known. TAF10 (TATA-Box Binding Protein Associated Factor 10) is the protein that coordinates activities for the initiation of transcription by RNA polymerase II required for activities of more than 70 polypeptides. TFIID binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as co-activators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the small subunits of TFIID that is associated with a subset of TFIID complexes. Studies with human and mammalian cells have shown that this subunit is required for transcriptional activation by the estrogen receptor, for progression through the cell cycle, and may also be required for certain cellular differentiation programs. Anti-TAF10 Antibody is useful for researchers interested in Chromatin research, transcription factor activity research, and DNA binding and transcription co-activator activity research. |
Immunogen | TAF10 antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to C-Terminal portion of human TAF10. |
Other Names | rabbit anti-TAF10 antibody, rabbit anti-Transcription initiation factor TFIID subunit 10 antibody, TAF-10, TAF 10, TAF2A, TAF2H, TAFII30, STAF28, Transcription initiation factor TFIID 30 kDa subunit, TAF(II)30, TAFII-30 |
Gene, Accession # | TAF10, Gene ID: 6881, NCBI: NP_006275.1, UniProt: Q12962 |
Catalog # | 600-401-GW8 |
Price | $475 |
Order / More Info | TAF10 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |