Serotonin Receptor 1B Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | Serotonin Receptor 1B |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | Protein G purified |
| Size | 100 µg |
| Concentration | 1.0 mg/mL |
| Applications | Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-Serotonin Receptor 1B Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Anti-Serotonin Receptor 1B from human, mouse and rat based on 100% homology with the immunizing sequence. Cross-reactivity with Anti-Serotonin Receptor 1B from other sources has not been determined. Anti-Serotonin Receptor 1B antibody detects rat Serotonin Receptor 1B. Serotonin (5-hydroxytryptamine, 5-HT), originally discovered as a serum factor plays important roles in regulating diverse biological processes in central and peripheral nervous systems, cardiovascular systems, and gastrointestinal systems. Molecular cloning studies have identified 5 receptors belonging to the 5-HT1 subtypes. These receptors are negatively coupled to adenylyl cyclase. Radioligand binding studies suggest the presence of 5-HT1B (formerly known as 5-HT1DbR) sites in substantia nigra, dorsal subiculum, globus pallidus, and superior collicum. The in situ hybridization studies show abundance of 5-HT1BR mRNA in CA1 pyramidal cells of hippocampus, Purkinje cells of cerebellum, olfactory tubercle, subthalamic nucleus and somewhat lower levels in the caudate-putamen, cortical areas, thalamic and hypothalamic nuclei. Anti-Serotonin Receptor 1B antibody is ideal for investigators involved in neurobiology. |
| Immunogen | Serotonin Receptor 1B Antibody was produced from whole rabbit serum prepared by repeated immunizations with a mixture of synthetic peptides corresponding to two internal amino acid sequences in rat 5-HT1BR protein. |
| Other Names | 5ht1b |
| Gene, Accession # | Htr1b, Gene ID: 25075, NCBI: NP_071561.1, UniProt: P28564 |
| Catalog # | 200-401-I11 |
| Price | $525 |
| Order / More Info | Serotonin Receptor 1B Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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