Edit |   |
---|---|
Antigenic Specificity | NLGN2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-NLGN2 antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. NLGN2 antibody is human, mouse and rat reactive. At least two isoforms are known to exist; this antibody will detect both isoforms. NLGN2 antibody is predicted to not cross-react with other members of the NLGN protein family. Neuroligin 2 (NLGN2) is a member of a family of neuronal cell surface proteins that localize to the post-synaptic membrane (1,2). Neuroligins are thought to act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses (2). NLGN2 has been shown to control perisomatic inhibitory synapse maturation together with gephyrin and collybistin, thereby regulating GABA receptor clustering on neurons (3,4). NLGN2 also exhibits differential functions at different types of inhibitory synapses on the same postsynaptic neuron (5). |
Immunogen | Anti-NLGN2 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 19 amino acid peptide near the C-terminus of human NLGN2. |
Other Names | Neuroligin 2 |
Gene, Accession # | NLGN2, Gene ID: 57555, NCBI: NP_065846, UniProt: Q8NFZ4 |
Catalog # | 600-401-DC7 |
Price | $475 |
Order / More Info | NLGN2 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |