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Antigenic Specificity | ALDH5A1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-Aldh5A1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with Aldh5A1 from other sources has not been determined. Aldh5A1 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. Aldehyde dehydrogenase enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. Aldh5A1 is a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, results in a disorder of the neurotransmitter 4-aminobutyric acid (GABA). Symptoms usually include static encephalopathy, associated with developmental delays, hypotonia, ataxia, speech defects, and seizures. At least two isoforms of Aldh5A1 are known to exist. |
Immunogen | Anti-Aldh5A1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 22 amino acid synthetic peptide near the C-terminus of the human Aldh5A1. |
Other Names | Aldh5A1 Antibody, SSDH, SSADH, Succinate-semialdehyde dehydrogenase, mitochondrial, Aldehyde dehydrogenase family 5 member A1 |
Gene, Accession # | ALDH5A1, Gene ID: 7915, NCBI: NP_733936, UniProt: P51649 |
Catalog # | 600-401-Y04 |
Price | $475 |
Order / More Info | ALDH5A1 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |