Edit |   |
---|---|
Antigenic Specificity | AP3M1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-AP3M1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. AP3M1 antibody may cross-react with AP3M2. The AP3 complex is a heterotetramer composed of two large adaptins (AP3D1, AP3B1 or AP3B2), a medium adaptin (AP3M1 or AP3M2) and a small adaptin (APS1 or AP3S2). The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. AP3M1 is highly homologous to AP3M2 but is the preferred binding partner to the YQRL motif from the cytosolic domain of TGN38. AP3M1 has also been shown to interact with the HIV-1 virulence protein Nef. |
Immunogen | Anti-AP3M1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 15 amino acid synthetic peptide near the C-terminus of human AP3M1. |
Other Names | AP3M1 Antibody, AP-3 complex subunit mu-1, AP-3 adapter complex mu3A subunit |
Gene, Accession # | AP3M1, Gene ID: 26985, NCBI: NP_036227, UniProt: Q9Y2T2 |
Catalog # | 600-401-Y24 |
Price | $475 |
Order / More Info | AP3M1 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |