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Antigenic Specificity | WAVE1-Scar |
Clone | S91-36 |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | Protein G purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | Immunohistochemistry, IF Microscopy, Immunoprecipitation, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-WAVE1-Scar Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with WAVE1-Scar from Mouse, Human, and Rat based on 100% homology with the immunizing sequence. Cross-reactivity with WAVE1-Scar from other sources has not been determined. Neuroscience research. The Wiskott-Aldrich syndrome protein (WASP) family plays essential roles in the regulation of actin polymerization. There are five WASP family members: Wasp, N-WASP, Wave1 (WASP family verprolin-homologous protein 1), WAVE2 and WAVE3. The Wasp family proteins share a conserved C-terminal region called the verprolin homology, cofilin homology and acidic domain. The Wave/Scar family of proteins mediates signals to actin assembly by direct activation of the Arp2/3 complex. These proteins have been characterized as major regulators of lamellipodia formation downstream of Rac activation, and as members of large protein complexes. IT has been found that all three Scar/Wave isoforms behave similarly and are likely to participate in the same kinds of protein complexes. |
Immunogen | WAVE1-Scar Antibody was produced in mice by repeated immunizations raised against a synthetic peptide corresponding to the near c-terminal region of human Wave1/Wasp family1. |
Other Names | Wave1, Scar1, WASP, Wave, WASF1, Wiskott-Aldrich syndrome protein family member 1, WASP family protein member 1, Verprolin homology domain-containing protein 1 |
Gene, Accession # | WASF1, Gene ID: 8936, NCBI: NP_001020105.1, UniProt: Q92558 |
Catalog # | 200-301-G64 |
Price | $485 |
Order / More Info | WAVE1-Scar Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |