WAVE1-Scar Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityWAVE1-Scar
CloneS91-36
Host SpeciesMouse
Reactive Specieshuman, mouse, rat
IsotypeIgG1
FormatProtein G purified
Size100 µg
Concentration1 mg/mL
ApplicationsImmunohistochemistry, IF Microscopy, Immunoprecipitation, Western Blot
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DescriptionAnti-WAVE1-Scar Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with WAVE1-Scar from Mouse, Human, and Rat based on 100% homology with the immunizing sequence. Cross-reactivity with WAVE1-Scar from other sources has not been determined. Neuroscience research. The Wiskott-Aldrich syndrome protein (WASP) family plays essential roles in the regulation of actin polymerization. There are five WASP family members: Wasp, N-WASP, Wave1 (WASP family verprolin-homologous protein 1), WAVE2 and WAVE3. The Wasp family proteins share a conserved C-terminal region called the verprolin homology, cofilin homology and acidic domain. The Wave/Scar family of proteins mediates signals to actin assembly by direct activation of the Arp2/3 complex. These proteins have been characterized as major regulators of lamellipodia formation downstream of Rac activation, and as members of large protein complexes. IT has been found that all three Scar/Wave isoforms behave similarly and are likely to participate in the same kinds of protein complexes.
ImmunogenWAVE1-Scar Antibody was produced in mice by repeated immunizations raised against a synthetic peptide corresponding to the near c-terminal region of human Wave1/Wasp family1.
Other NamesWave1, Scar1, WASP, Wave, WASF1, Wiskott-Aldrich syndrome protein family member 1, WASP family protein member 1, Verprolin homology domain-containing protein 1
Gene, Accession #WASF1, Gene ID: 8936, NCBI: NP_001020105.1, UniProt: Q92558
Catalog #200-301-G64
Price$485
Order / More InfoWAVE1-Scar Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

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