Edit |   |
---|---|
Antigenic Specificity | CD81 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1.0 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-CD81 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with CD81 from other sources has not been determined. CD81 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family, a group of cell-surface proteins that are characterized by the presence of four hydrophobic domains and mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD81 is a cell surface glycoprotein that associates with integrins and appears to promote muscle cell fusion and support myotube maintenance. Along with SCARB1, LDL-R, and CLDN1, CD81 has been reported to be an entry factor for the Hepatitis C virus. Finally, recent evidence indicates that the CD81 gene is localized in a tumor-suppressor gene region and is thus a candidate gene for malignancies. |
Immunogen | Anti-CD81 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 20 amino acid synthetic peptide near the N-terminus of human CD81. |
Other Names | CD81 Antibody, S5.7, CVID6, TAPA1, TSPAN28, CD81 antigen, 26 kDa cell surface protein TAPA-1, Tspan-28 |
Gene, Accession # | CD81, Gene ID: 975, NCBI: NP_004347, UniProt: P60033 |
Catalog # | 600-401-AJ2 |
Price | $475 |
Order / More Info | CD81 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |