FAM129B Phospho S679/689 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | FAM129B Phospho S679/689 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | immunoaffinity purified, no preservative |
| Size | 100 µL |
| Concentration | n/a |
| Applications | ELISA, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-Phospho-Ser679/683 FAM129B Antibody is directed against human FAM129B protein phosphorylated at S679 and S683. The antibody was prepared from monospecific antiserum by immunoaffinity chromatography using phospho peptide coupled to agarose beads followed by solid phase adsorption(s) against non-phospho peptide and non-specific peptide to remove any unwanted reactivities. Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Rabbit Serum. This antibody is specific for phosphorylated FAM129B. Minimal reactivity occurs against non-phosphorylated FAM129B. Reactivity against FAM129B occurs from mouse sources. However, reactivity is also expected against human and non-human primate based on 100% sequence homology. FAM129B, also known as Niban-like protein 1, belongs to a poorly characterized protein family with unknown category and function. Increased expression of the Niban gene has been observed in renal carcinomas. Suppression of FAM129B expression in HeLa cells has been seen to promote apoptosis, suggesting that it can modulate cell death signaling, and may be involved in the ER stress response. FAM129B is also up-regulated in various types of thyroid tumors and Hashimoto's thyroiditis. It has been suggested that the MAP kinase dependent phosphorylation of FAM129B is important in controlling melanoma cells, as inhibition of B/Raf/MKK/ERK in melanoma cells represses invasion. It is believed that phosphorylated FAM129B not only derepresses invasion, but also regulates events that promote invasion. FAM129B pS679/683 Antibody is ideal for researchers interested in cancer research. |
| Immunogen | Anti-Phospho-Ser679/683 FAM129B Antibody was produced in rabbits by repeated immunizations with a synthetic phospho-peptide corresponding to amino acid residues surrounding Ser679/683 of human FAM129B conjugated to KLH. |
| Other Names | Niban-like protein 1, Meg-3, Melanoma invasion by ERK, MINERVA, Protein FAM129B |
| Gene, Accession # | FAM129B, Gene ID: 64855, NCBI: NP_001030611.1, UniProt: Q96TA1 |
| Catalog # | 600-401-X06 |
| Price | $475 |
| Order / More Info | FAM129B Phospho S679/689 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
Profile of ROCKLAND IMMUNOCHEMICALS INC.