ZFP281 Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityZFP281
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatimmunoaffinity purified
Size100 µg
Concentration1 mg/mL
ApplicationsELISA, IF Microscopy, Western Blot
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DescriptionAnti-ZFP281 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with ZFP281 from other sources has not been determined. ZFP281, also known as ZBP-99, is a member of a conserved family of transcription factors that interact with GC-rich promoters. It contains four Kruppel-like zinc fingers and is highly homologous to ZBP-89, another regulator of ornithine decarboxylase gene expression. ZFP281 also interacts with many other transcription factors, such as Sp1 to repress vimentin gene transcription. ZFP281 has also been shown to control embryonic stem cell pluripotency by direct regulating specific target genes. ZFP281 physically interacts with the transcription factors POU5F1, Sox2, and NANOG. Gene expression microarray analysis indicated that some ZFP281 target genes were activated, while others were repressed upon knockdown of ZFP281 expression, showing that ZFP281 plays bifunctional roles in regulating gene expression in stem cells.
ImmunogenAnti-ZFP281 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 19 amino acid synthetic peptide near the C-terminus of human ZFP281.
Other NamesZFP281 Antibody, ZBP-99, ZNP-99, GZP1, ZBP99, Zinc finger protein 281, GC-box-binding zinc finger protein 1
Gene, Accession #ZNF281, Gene ID: 23528, NCBI: NP_001268222.1, UniProt: Q9Y2X9
Catalog #600-401-GD4
Price$475
Order / More InfoZFP281 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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