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Antigenic Specificity | HDAC3 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | Protein A purified |
Size | 50 µg |
Concentration | 2 mg/ml |
Applications | Chip, IF Microscopy |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-HDAC3 Antibody was purified by Protein A chromatography. Cross-reactivity with HDAC3 from other sources has not been determined. HDAC3 catalyses the deacetylation of lysine residues in the N-terminal part of the core histones (H2A, H2B, H3 and H4). Acetylation and deacetylation of these highly conserved lysine residues is important for the control of gene expression and HDAC activity is associated with gene repression. Histone deacetylation is established by the formation of large multiprotein complexes. HDAC3 may bind to the zinc-finger transcription factor YY1, thereby regulating transcription. It is also able to modulate cell growth and apoptosis through the interaction with p53 and is thought to be essential for the repression of the POU1F1 transcription factor. Anti-HDAC3 Antibody is ideal for research in Epigenetics and Gene Expression. |
Immunogen | Anti-HDAC3 Antibody was produced in mice by repeated immunization with a synthetic peptide containing a sequence from the C-terminal region of the human HDAC3 protein. |
Other Names | HD3, RPD3-2, SMAP45 |
Gene, Accession # | HDAC3, Gene ID: 8841, NCBI: NP_003874.2, UniProt: O15379 |
Catalog # | 200-301-V03 |
Price | $485 |
Order / More Info | HDAC3 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |