IRF4 Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityIRF4
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunoaffinity purified
Size100 µg
Concentration1.0 mg/ml
ApplicationsELISA, IF Microscopy, Western Blot
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DescriptionAnti-IRF4 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. IRF4 antibody is predicted to not cross-react with other IRF protein family members. IRF4 often migrates at a higher than predicted molecular weight in SDS-PAGE. Interferons (IFNs) are involved in a multitude of immune interactions during viral infections and play a major role in both the induction and regulation of innate and adaptive antiviral mechanisms. During infection, host-virus interactions signal downstream molecules such as transcription factors such as IFN regulatory factor-3 (IRF3) which can act to stimulate transcription of IFN-alpha/beta genes. Another member, IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. IRF4 expression is tightly regulated in resting primary T cells and plays an essential role in the homeostasis and function of mature lymphocytes. IRF4 is induced by Toll-like receptor (TLR) activation and acts as a negative regulator of TLR signaling.
ImmunogenAnti-IRF4 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 16 amino acid synthetic peptide near the C-terminus of human IRF4.
Other NamesIRF4 Antibody, MUM1, LSIRF, NF-EM5, MUM1, Interferon regulatory factor 4, Lymphocyte-specific interferon regulatory factor, IRF-4
Gene, Accession #IRF4, Gene ID: 3662, NCBI: NP_002451, UniProt: Q15306
Catalog #600-401-CA3
Price$475
Order / More InfoIRF4 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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