CD8a Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | CD8a |
| Clone | HIT8a |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 kappa |
| Format | fluorescein (FITC) conjugate |
| Size | 500 µL |
| Concentration | n/a |
| Applications | Flow Cytometry, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Fluorescein conjugated CD8a Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against human CD8a. Reactivity is observed against human CD8a, Marmoset, and chimpanzee. This clone recognizes the alpha chain of CD85. It does not block the binding of RPA-T8 antibody to CD8a. Cross reactivity with CD8a from other sources has not been tested. Anti-CD8a is conjugated with FITC under optimal conditions and the solution is free of unconjugated FITC. CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck. |
| Immunogen | Anti-CD8a Antibody (Monoclonal) was produced by repeated immunizations with CD8a antigen. |
| Other Names | T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2, CD8a |
| Gene, Accession # | CD8A, Gene ID: 925, NCBI: NP_001139345.1, UniProt: P01732 |
| Catalog # | 200-302-N61 |
| Price | $315 |
| Order / More Info | CD8a Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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