PHOX2A Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | PHOX2A |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 100 µg |
| Concentration | 1 mg/mL |
| Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-PHOX2A Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. PHOX2A antibody is predicted to not cross-react with other paired homeobox family members. PHOX2A and PHOX2B (Paired mesoderm homeobox protein) are closely related, paired-homeodomain transcription factors that function as determinants of the noradrenergic phenotype during embryogenesis. PHOX2 proteins are crucial for the regulation of endogenous hydroxylases in neural crest cells and promote sympathetic neuron generation. Human PHOX2B contains one DNA binding homeobox domain and is required for the differentiation of all central and nonperipheral noradrenergic centers in the brain. In contrast, PHOX2A controls only the differentiation of the main noradrenergic center of the brain. Regulation of PHOX2 may have therapeutic utility in aging or disorders involving degeneration of noradrenergic neurons. |
| Immunogen | Anti-PHOX2A antibody was prepared from whole rabbit serum produced by repeated immunizations with a 16 amino acid synthetic peptide near the C-terminus of human PHOX2A. |
| Other Names | PHOX2A Antibody, ARIX, FEOM2, NCAM2, PMX2A, CFEOM2, ARIX, Paired mesoderm homeobox protein 2A, ARIX1 homeodomain protein |
| Gene, Accession # | PHOX2A, Gene ID: 401, NCBI: NP_005160, UniProt: O14813 |
| Catalog # | 600-401-DM4 |
| Price | $475 |
| Order / More Info | PHOX2A Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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