ECRG4 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | ECRG4 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 100 µg |
| Concentration | 1.0 mg/ml |
| Applications | ELISA, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-ECRG4 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. ECRG4 antibody is predicted to not cross-react with other ECRG family members. The esophageal cancer-related gene 4 (ECRG4), also known as Augurin, was identified through differential display screening between esophageal cancer and normal tissue. Hypermethylation of CpG sites in the ECRG4 promoter correlate with ECRG4 downregulation in numerous esophageal squamous cell carcinoma tissues. In transfected cells, overexpression of ECRG4 induced G1 arrest, dephosphorylation of Rb and decreased expression of cyclins D1 and D3. Increased expression of ECRG4 in aged mouse brain is observed compared with young mouse brain. The increased ECRG4 level was accompanied by elevated senescence-associated acidic beta-galactosidase activity, suggesting that ECRG4 is involved in cellular differentiation and senescence. |
| Immunogen | Anti-ECRG4 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 20 amino acid synthetic peptide near the C-terminus of human ECRG4. |
| Other Names | ECRG4 Antibody, ECRG4, ECRG4, UNQ761/PRO1508, Augurin, Esophageal cancer-related gene 4 protein |
| Gene, Accession # | C2orf40, Gene ID: 84417, NCBI: AAI09386, UniProt: Q9H1Z8 |
| Catalog # | 600-401-AY9 |
| Price | $475 |
| Order / More Info | ECRG4 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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