NMDA R2A phospho Y1325 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | NMDA R2A phospho Y1325 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse, rat |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 100 µL |
| Concentration | n/a |
| Applications | Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti NMDA R2A pY1325 antibody is directed against NMDA R2A protein. The antibody was affinity purified from monospecific antiserum by immunoaffinity purification. The antibody is specific for the protein phosphorylated at Y1325. Immunolabeling is completely blocked by the phosphopeptide used as the antigen but not by the corresponding dephosphopeptide. Reactivity is expected from mouse. Cross reactivity with NMDA R2A from other species has not been determined. NMDA R2A pY1325 Antibody detects NMDA R2A protein. The ion channels activated by glutamate that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR). The NMDAR plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer's, epilepsy and ischemic neuronal cell death. The NMDA receptor is also one of the principal molecular targets for alcohol in the CNS. Channels with physiological characteristics are produced when the NR1 subunit is combined with one or more of the NMDAR2 (NR2 A-D) subunits. Recently, phosphorylation of Tyrosine 1325 of the NR2A subunit has been shown to be increased in human brain tissue sections from HIV-infected individuals with encephalitis. In addition, Tyr1325 phosphorylation has been linked with depression-related behavior. Anti-NMDA R2A pY1325 Antibody is ideal for investigators involved in Neuroscience, Signal Transduction, and Cell Signaling Research. |
| Immunogen | Anti-NMDA R2A pY1325 Antibody was produced by repeated immunizations with a synthetic phospho-peptide corresponding to amino acid residues surrounding Tyr1325. |
| Other Names | Glutamate [NMDA] receptor subunit epsilon-1, N-methyl D-aspartate receptor subtype 2A, NMDAR2A, NR2A, Grin2a |
| Gene, Accession # | Grin2a, Gene ID: 24409, UniProt: Q00959 |
| Catalog # | 600-401-D90 |
| Price | $475 |
| Order / More Info | NMDA R2A phospho Y1325 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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