Cu/Zn SOD Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | Cu/Zn SOD |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat, bovine |
| Isotype | n/a |
| Format | affinity purified |
| Size | 100 µg |
| Concentration | 1.0 mg/mL |
| Applications | ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-Cu/Zn SOD Antibody was purified by affinity chromatography. A BLAST analysis was used to suggest cross-reactivity with Cu/Zn SOD from Human, Rat, Mouse, and Bovine based on 100% homology with the immunizing sequence. Cross-reactivity with Cu/Zn SOD from other sources has not been determined. Oxidative stress research. Superoxide dismutase (SOD) is an endogenously produced intracellular enzyme present in almost every cell in the body. It works by catalyzing the dismutation of the superoxide radical O2? to O2 and H2O2, which are then metabolized to H2O and O2 by catalase and glutathione peroxidase. In general, SODs play a major role in antioxidant defense mechanisms. There are two main types of SOD in mammalian cells. One form (SOD1) contains Cu and Zn ions as a homodimer and exists in the cytoplasm. The two subunits of 16 kDa each are linked by two cysteines forming an intra-subunit disulphide bridge (3). The second form (SOD2) is a manganese containing enzyme and resides in the mitochondrial matrix. It is a homotetramer of 80 kDa. The third form (SOD3 or EC-SOD) is like SOD1 in that it contains Cu and Zn ions, however it is distinct in that it is a homotetramer, with a mass of 30 kDA and it exists only in the extra-cellular space. SOD3 can also be distinguished by its heparin-binding capacity. |
| Immunogen | Cu/Zn SOD Antibody was produced from whole rabbit serum prepared by repeated immunizations with a synthetic peptide corresponding to rat Cu/Zn SOD. |
| Other Names | Superoxide dismutase1, Superoxide dismutase Cu-Zn, ALS1, IPOA, SOD1, SOD2, SODC, hSod1 |
| Gene, Accession # | Sod1, Gene ID: 24786, NCBI: NP_058746.1, UniProt: P07632 |
| Catalog # | 600-401-F19 |
| Price | $455 |
| Order / More Info | Cu/Zn SOD Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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