IKB alpha Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Search, find, compare suppliers for anti-IKB alpha antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | IKB alpha |
| Clone | 6A920 |
| Host Species | Mouse |
| Reactive Species | human, mouse |
| Isotype | IgG1 kappa |
| Format | Protein G purified |
| Size | 100 µg |
| Concentration | 1.0 mg/mL |
| Applications | Flow Cytometry, Immunoprecipitation, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-IkBα Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with IkBα from Human and Mouse based on 100% homology with the immunizing sequence. Cross-reactivity with Anti-IkBα from other sources has not been determined. Anti-IkB alpha detects human IkB alpha. NF-kB is silenced in the cytoplasm by an inhibitory protein, IkB. Synthesis of IkBa is autoregulated. IkB proteins are phosphorylated by IkB kinase complex consisting of at least three proteins, IKK1/a, IKK2/b, and IKK3/g. External stimuli such as tumor necrosis factor or other cytokines results in phosphorylation and degradation of IkB releasing NF-kB dimers. NF-kB dimer subsequently translocates to the nucleus and activates target genes. Six members of IkB family members have been identified. One of the first gene induced following NF-kB activation is IkBa. Anti-IkB alpha antibody is ideal for investigators involved in NFkappaB, kinase and phosphatase research. |
| Immunogen | IkB alpha Antibody was produced in mice prepared by repeated immunizations of recombinant protein corresponding to internal amino acids in the human IkB alpha protein. |
| Other Names | IKBA, MAD3, NFKBI, NF-kappa-B inhibitor alpha, I-kappa-B-alpha, IkB-alpha, IkappaBalpha, Major histocompatibility complex enhancer-binding protein MAD3 |
| Gene, Accession # | NFKBIA, Gene ID: 4792, NCBI: NP_065390.1, UniProt: P25963 |
| Catalog # | 200-301-H80 |
| Price | $549 |
| Order / More Info | IKB alpha Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
Profile of ROCKLAND IMMUNOCHEMICALS INC.
Return to Antibodies