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Antigenic Specificity | UCP1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-UCP1 antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. UCP1 antibody is human, mouse and rat reactive. The mitochondrial brown fat uncoupling protein 1 (UCP1) is a member of the family of mitochondrial anion carrier proteins (MACP) (1). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells (1). UCP1 is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat (1). |
Immunogen | Anti-UCP1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 17 amino acid peptide near the C-terminus of human UCP1 (GenBank accession. |
Other Names | UCP1 Antibody, UCP, SLC25A7, UCP, Mitochondrial brown fat uncoupling protein 1, Solute carrier family 25 member 7, UCP 1 |
Gene, Accession # | UCP1, Gene ID: 7350, NCBI: NP_068605.1, UniProt: P25874 |
Catalog # | 600-401-FT9 |
Price | $475 |
Order / More Info | UCP1 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |