NALP4 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | NALP4 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 100 µg |
| Concentration | 1 mg/mL |
| Applications | ELISA, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-NALP4 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with NALP4 from other sources has not been determined. NALP proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins and are thought to be involved in inflammation and reproduction. NALP4, also known as PYRIN-containing APAF1-like protein 4, has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. In transfected 293 cells, NALP4 suppressed NF-kB induction by TNF-a and IL-1b, suggesting NALP4 operates at a point of convergence in these two signaling pathways. NALP4 also suppressed NF-kB induction resulting from overexpression of several adapter proteins and protein kinases involved in these pathways, including TRAF2, TRAF6, RIP, and IRAK2, as well as the IKK-alpha and IKK-beta, suggesting that NALP4 is critical in modulating NF-kB activity. |
| Immunogen | Anti-NALP4 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 13 amino acid synthetic peptide near the internal region of human NALP4. |
| Other Names | NALP4 Antibody, CT58, PAN2, RNH2, NALP4, PYPAF4, CLR19.5, NACHT, LRR and PYD domains-containing protein 4, PAAD and NACHT-containing protein 2, CT58 |
| Gene, Accession # | NLRP4, Gene ID: 147945, NCBI: AAL35293, UniProt: Q96MN2 |
| Catalog # | 600-401-CY2 |
| Price | $475 |
| Order / More Info | NALP4 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
Profile of ROCKLAND IMMUNOCHEMICALS INC.
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