Edit |   |
Antigenic Specificity | TRIM33 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-TRIM33 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. TRIM33 antibody is human, mouse and rat reactive. At least two isoforms of TRIM33 are known to exist. TRIM24 (TIF1alpha), TRIM28 (TIF1beta), and TRIM33 (TIF1gamma) are three related cofactors belonging to the tripartite motif superfamily that interact with distinct transcription factors (1-2). The structure of TRIM33 is similar to TRIM24 and TRIM28, exhibiting multiple domains (RING finger, coiled coil, B boxes, PHD/TTC, and bromodomain) (3). TRIM33 functions in cell differentiation and development, playing a role in differentiation of hematopoietic cells (3). It interacts with the Smad2/3 transcription factor in hematopoietic, mesenchymal, and epithelial cell types to mediate different transcriptional effects in response to TGF-beta (4). It acts as an E3 ubiquitin-protein ligase and promotes SMAD4 ubiquitination (5). |
Immunogen | Anti-TRIM33 antibody was prepared from whole rabbit serum produced by repeated immunizations with an 18 amino acid peptide near the internal region of human TRIM33. |
Other Names | TRIM33 Antibody, ECTO, PTC7, RFG7, TF1G, TIF1G, TIFGAMMA, TIF1GAMMA, KIAA1113, E3 ubiquitin-protein ligase TRIM33, Ectodermin homolog, Protein Rfg7 |
Gene, Accession # | TRIM33, Gene ID: 51592, NCBI: NP_056990.3, UniProt: Q9UPN9 |
Catalog # | 600-401-FP5 |
Price | $475 |
Order / More Info | TRIM33 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |