Neuromodulin phospho S41 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | Neuromodulin phospho S41 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse, rat |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 100 µL |
| Concentration | n/a |
| Applications | Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-GAP43 pS41 antibody was affinity purified from monospecific antiserum by immunoaffinity purification. This antibody is specific for the phosphorylated forms of the protein. Immunolabeling is completely eliminated by treatment with lambda-Ptase. Cross reactivity with GAP43 from other species has not been determined, however, the sequence of the immunogen shows 100% homology to bovine, canine, chicken, finch, human, mouse, non-human primates, Xenopus and zebra fish. Gap-43 pS41 antibody detects phosphorylated GAP43 at position S41. Gap43 is thought to have an important role in development and plasticity because it is expressed at high levels in neuronal growth cones during development and during axonal regeneration. There is also evidence from knockout animals that Gap-43 serves to amplify pathfinding signals from the growth cone. Gap-43 is thought to mediate at least some of these effects via interaction with actin. Importantly, phosphorylation at Ser41 by protein kinase C modulates the interaction of Gap-43 with actin and may also affect neurotransmitter release during forms of plasticity like LTP. Anti-Gap-43 pS41 antibody is ideal for investigators involved in Cell Signaling, Neuroscience, and Signal Transduction research. |
| Immunogen | Anti-Neuromodulin Antibody was produced by repeated immunizations with a synthetic phospho-peptide corresponding to amino acid residues surrounding Ser41 of GAP43. |
| Other Names | Neuromodulin, Axonal membrane protein GAP-43, GAP43, Growth-associated protein 43, Protein F1, Neural phosphoprotein B-50, pp46 |
| Gene, Accession # | Gap43, Gene ID: 29423, UniProt: P07936 |
| Catalog # | 612-401-D59 |
| Price | $475 |
| Order / More Info | Neuromodulin phospho S41 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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