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Antigenic Specificity | Tslp Receptor |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-TSLP Receptor Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with TSLP Receptor from other sources has not been determined. Thymic stromal lymphopoietin (TSLP) has recently been identified as an important factor capable of driving dendritic cell maturation and activation. It is involved in the positive selection of regulatory T cells, maintenance of peripheral CD4+ T cell homeostasis and the induction of CD4+ T cell-mediated allergic reaction. TSLP is also capable of supporting the growth of fetal liver and adult B cell progenitors and their differentiation to the IgM-positive stage of B cell development. Its receptor TSLP-R will bind TSLP in a low-affinity fashion in transfected cells; co-transfection with IL-7R-alpha cDNA results in high-affinity binding and a functional heteromeric complex. This heteromeric receptor requires stat5 for TSLP-mediated signal transduction and is inhibited by SOCS-1. The approximately 75 kDa band seen in the immunoblot may be a post-translationally modified form of TSLP-R. |
Immunogen | Anti-TSLP receptor antibody was prepared from whole rabbit serum produced by repeated immunizations with a 21 amino acid synthetic peptide from near the internal region of mouse TSLP receptor. |
Other Names | TSLP Receptor Antibody, CRLM2, Ly114, Tpte2, Tslpr, Crlm2, Cytokine receptor-like factor 2, Cytokine receptor-like molecule 2, CRLM-2 |
Gene, Accession # | Crlf2, Gene ID: 10194, NCBI: NP_005777, UniProt: Q8CII9 |
Catalog # | 600-401-FR9 |
Price | $475 |
Order / More Info | Tslp Receptor Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |