SIRT1 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | SIRT1 |
| Clone | polyclonal |
| Host Species | Chicken |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 100 µg |
| Concentration | 1 mg/mL |
| Applications | ELISA, IF Microscopy, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-SIRT1 Antibody is an IgY fraction that has been affinity purified by immunoaffinity purification. Cross reactivity with SIRT1 from other sources has not been determined. The Silent Information Regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and have important functions in the regulation of metabolism, growth and differentiation, inflammation, cellular survival, as well as in senescence and lifespan extension. Sirtuins, including SIRT1-7, are human homologs of yeast Sir2p. Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) which regulate cellular metabolism, e.g. energy metabolism, and thereby are associated with aging and several age-related diseases. SIRT1 has the closest homology to the yeast Sir2p and is widely expressed in fetal and adult tissues. SIRT1 regulates the p53-dependent DNA damage response pathway by binding to and deacetylating p53, specifically via lysine residue. |
| Immunogen | Anti-SIRT1 antibody was prepared from chicken egg fractions produced by repeated immunizations with a 19 amino acid synthetic peptide near the N-terminus of human SIRT1. |
| Other Names | SIRT1 Antibody, SIR2L1, SIR2L1, NAD-dependent protein deacetylase sirtuin-1, Regulatory protein SIR2 homolog 1, hSIRT1 |
| Gene, Accession # | SIRT1, Gene ID: 23411, NCBI: NP_036370, UniProt: Q96EB6 |
| Catalog # | 200-901-EL5 |
| Price | $475 |
| Order / More Info | SIRT1 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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