CD86 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | CD86 |
| Clone | IT2.2 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2b kappa |
| Format | allophycocyanin (APC) conjugate |
| Size | 500 µL |
| Concentration | n/a |
| Applications | Flow Cytometry, Immunohistochemistry, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Allophycocyanin conjugated CD86 Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against human CD86. Reactivity is observed against human CD86. Cross reactivity is observed with Baboon, Capuchin Monkey, Common Marmoset, Cotton-topped Tamarin, Chimpanzee, Cynomolgus, and Rhesus. Reactivity with CD86 from other sources has not been tested. Anti-CD86 is conjugated with APC under optimal conditions and the solution is free of unconjugated APC. CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, monocytes/macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is the ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce costimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells. |
| Immunogen | Anti-CD86 Antibody (Monoclonal) was produced by repeated immunizations with CD86 antigen. |
| Other Names | T-lymphocyte activation antigen CD86, Activation B7-2 antigen, B70, BU63, CTLA-4 counter-receptor B7.2, FUN-1, CD86, CD28LG2 |
| Gene, Accession # | CD86, Gene ID: 942, NCBI: NP_001193853.1, UniProt: P42081 |
| Catalog # | 200-326-N75 |
| Price | $585 |
| Order / More Info | CD86 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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