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Antigenic Specificity | MINA |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-MINA Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with MINA from other sources has not been determined. MINA is nuclear localized, myc-inducible protein that is thought to play a role in mammalian cell proliferation. Treatment of cancer cells lines such as the colon cancer cell line SW680 with siRNA against MINA inhibits cell growth, demonstrating that MINA may be a potential therapeutic target. MINA regulates several genes related to cell adhesion and metabolism that have also been shown to be regulated by c-Myc, but also regulates other genes whose expression are not modulated by c-Myc such as EGFR, IL-6 and HGF. MINA has also been found to act as a repressor to IL-4 expression in T cells, indicating that it may also play a role in T cell differentiation and genetic variation in T helper type 2 bias. |
Immunogen | Anti-MINA antibody was prepared from whole rabbit serum produced by repeated immunizations with a 15 amino acid synthetic peptide near the N-terminus of human MINA. |
Other Names | Ribosomal oxygenase 2, 60S ribosomal protein L27a histidine hydroxylase, Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA (EC:1.14.11.-), Histone lysine demethylase MINA, MYC-induced nuclear antigen, Mineral dust-induced gene protein, Nucleolar protein 52, Ribosomal oxygenase MINA, ROX, RIOX2, MDIG, MINA, MINA53, NO52 |
Gene, Accession # | RIOX2, Gene ID: 84864, NCBI: NP_694822, UniProt: Q8IUF8 |
Catalog # | 600-401-CU6 |
Price | $475 |
Order / More Info | MINA Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |