ZGPAT Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityZGPAT
Clonepolyclonal
Host SpeciesChicken
Reactive Specieshuman
Isotypen/a
Formatimmunoaffinity purified
Size100 µg
Concentration1 mg/mL
ApplicationsELISA, IF Microscopy, Western Blot
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DescriptionAnti-ZGPAT Antibody is an IgY fraction that has been affinity purified by immunoaffinity purification. Multiple isoforms of ZGPAT are known to exist. The Zinc finger CCCH-type with G patch domain-containing protein (ZGPAT), is a transcriptional repressor that regulates several cellular pathways including EGFR pathways that are involved in cell proliferation, migration and survival. ZGPAT recruits the Mi-2/NuRD complex and represses the expression of EGFR. ZGPAT is down-regulated in breast carcinomas and its expression is negatively correlated with that of EGFR, suggesting that it may be a potential target for breast cancer therapy. Multiple isoforms of ZGPAT are known to exist, including sZIP, which binds to the Mi-2/NuRD complex but lacks the DNA binding component of full-length ZGPAT, thereby antagonizing transcription repression and growth inhibition by ZGPAT.
ImmunogenAnti-ZGPAT antibody was prepared from chicken egg fractions produced by repeated immunizations with a 15 amino acid synthetic peptide near the C-terminus of human ZGPAT.
Other NamesZGPAT Antibody, ZIP, ZC3H9, GPATC6, GPATCH6, ZC3HDC9, KIAA1847, ZIP, Zinc finger CCCH-type with G patch domain-containing protein, G patch domain-containing protein 6
Gene, Accession #ZGPAT, Gene ID: 84619, NCBI: NP_001076582.1, UniProt: Q8N5A5
Catalog #200-901-GD6
Price$475
Order / More InfoZGPAT Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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