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Antigenic Specificity | CD62L |
Clone | MEL-14 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2a kappa |
Format | phycoerythrin (RPE) conjugate |
Size | 200 µg |
Concentration | 0.2mg/mL |
Applications | Flow Cytometry, Immunohistochemistry, Immunoprecipitation |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Phycoerythrin conjugated CD62L Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against mouse CD62L. Cross reactivity with CD62L from other sources has not been tested. Anti-CD62L is conjugated with PE under optimal conditions and the solution is free of unconjugated PE. CD62L is a 74-95 kD glycoprotein also known as L-selectin, LECAM-1, Ly-22, LAM-1, and MEL-14. It is a member of the selectin family and is expressed on the majority of B and naive T cells, a subset of memory T cells, monocytes, granulocytes, most thymocytes, and a subset of NK cells. CD62L is important in lymphocyte homing to high endothelial venules (HEV) in peripheral lymph nodes and leukocyte "rolling" on activated endothelium. CD62L also contributes to neutrophil emigration at inflammatory sites. CD62L is rapidly shed from lymphocytes and neutrophils upon cellular activation and the expression levels of CD62L (in conjunction with other markers) have been used to distinguish naive, effector, and memory T cells. CD62L has been reported to interact with CD34, glyCAM-1, and MAdCAM-1. |
Immunogen | Anti-CD62L Antibody (Monoclonal) was produced by repeated immunizations with C3H/eb mouse B lymphoma 38C-13. |
Other Names | L-selectinCD62 antigen-like family member LLeukocyte adhesion molecule 1LAM-1Leukocyte-endothelial cell adhesion molecule 1LECAM1Lymph node homing receptorLymphocyte antigen 22Ly-22Lymphocyte surface MEL-14 antigenCD62L Sell Lnhr, Ly-22, Ly22 |
Gene, Accession # | Sell, Gene ID: 20343, NCBI: NP_035476.1, UniProt: P18337 |
Catalog # | 200-508-N87 |
Price | $495 |
Order / More Info | CD62L Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |