CD62L Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityCD62L
CloneMEL-14
Host SpeciesRat
Reactive Speciesmouse
IsotypeIgG2a kappa
Formatphycoerythrin (RPE) conjugate
Size200 µg
Concentration0.2mg/mL
ApplicationsFlow Cytometry, Immunohistochemistry, Immunoprecipitation
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DescriptionPhycoerythrin conjugated CD62L Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against mouse CD62L. Cross reactivity with CD62L from other sources has not been tested. Anti-CD62L is conjugated with PE under optimal conditions and the solution is free of unconjugated PE. CD62L is a 74-95 kD glycoprotein also known as L-selectin, LECAM-1, Ly-22, LAM-1, and MEL-14. It is a member of the selectin family and is expressed on the majority of B and naive T cells, a subset of memory T cells, monocytes, granulocytes, most thymocytes, and a subset of NK cells. CD62L is important in lymphocyte homing to high endothelial venules (HEV) in peripheral lymph nodes and leukocyte "rolling" on activated endothelium. CD62L also contributes to neutrophil emigration at inflammatory sites. CD62L is rapidly shed from lymphocytes and neutrophils upon cellular activation and the expression levels of CD62L (in conjunction with other markers) have been used to distinguish naive, effector, and memory T cells. CD62L has been reported to interact with CD34, glyCAM-1, and MAdCAM-1.
ImmunogenAnti-CD62L Antibody (Monoclonal) was produced by repeated immunizations with C3H/eb mouse B lymphoma 38C-13.
Other NamesL-selectinCD62 antigen-like family member LLeukocyte adhesion molecule 1LAM-1Leukocyte-endothelial cell adhesion molecule 1LECAM1Lymph node homing receptorLymphocyte antigen 22Ly-22Lymphocyte surface MEL-14 antigenCD62L Sell Lnhr, Ly-22, Ly22
Gene, Accession #Sell, Gene ID: 20343, NCBI: NP_035476.1, UniProt: P18337
Catalog #200-508-N87
Price$495
Order / More InfoCD62L Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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