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Antigenic Specificity | APPBP2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-APPBP2 antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. APPBP2 antibody is human, mouse and rat reactive. At least two isoforms of APPBP2 are known to exist; this antibody will detect both isoforms. The amyloid beta precursor protein (cytoplasmic tail) binding protein 2 (APPBP2), also known as PAT1, interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing (1). The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease (2). APPBP2 has been found to be highly expressed in breast cancer (3). |
Immunogen | Anti-APPBP2 antibody was prepared from whole rabbit serum produced by repeated immunizations with an 18 amino acid peptide near the C-terminus of human APPBP2. |
Other Names | APPBP2 Antibody, PAT1, APP-BP2, HS.84084, KIAA0228, PAT1, Amyloid protein-binding protein 2, Amyloid beta precursor protein-binding protein 2 |
Gene, Accession # | APPBP2, Gene ID: 10513, NCBI: NP_006371, UniProt: Q92624 |
Catalog # | 600-401-Y52 |
Price | $475 |
Order / More Info | APPBP2 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |