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Antigenic Specificity | USP25 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-USP25 antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. USP25 antibody is human and mouse reactive. Multiple isoforms of USP25 are known to exist. USP25 (ubiquitin specific peptidase 25), also known as USP21, belongs to the peptidase C19 family and is a highly conserved 76-amino acid protein involved in regulation of intracellular protein breakdown, cell cycle regulation, and stress response (1). It contains one UBA-like domain and two UIM (ubiquitin-interacting motif) repeats. Due to alternative splicing events, USP25 is expressed as two short, ubiquitously expressed isoforms and one long, muscle-specific isoform (2). The long isoform of USP25 (USP25m) is upregulated in myogenesis and is implicated in regulation of muscular differentiation and function. USP25 is a deubiquitinating enzyme (DUB) that negatively regulates IL-17-triggered signaling (3,4). |
Immunogen | Anti-USP25 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 17 amino acid peptide near the internal region of human USP25. |
Other Names | USP25 Antibody, USP21, USP21, Ubiquitin carboxyl-terminal hydrolase 25, Deubiquitinating enzyme 25 |
Gene, Accession # | USP25, Gene ID: 29761, NCBI: NP_001269970.1, UniProt: Q9UHP3 |
Catalog # | 600-401-FV6 |
Price | $475 |
Order / More Info | USP25 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |